Wednesday, 8 October 2025

Chronic Venous Insufficiency (CVI): Causes, Symptoms, Diagnosis, and Treatment

Chronic Venous Insufficiency (CVI) is a long-term circulatory condition that affects the veins in the legs. It occurs when the vein valves that help return blood from the legs to the heart become weak or damaged, leading to poor blood flow. As a result, blood pools in the lower extremities, creating high pressure inside the veins and causing pain, swelling, skin discoloration, and varicose veins.



Over time, if left untreated, CVI can lead to serious complications such as leg ulcers, infections, and permanent skin changes. Understanding its causes, symptoms, and treatment options can help manage the condition effectively and prevent progression.

What Causes Chronic Venous Insufficiency?

The primary reason CVI develops is malfunctioning or damaged vein valves. Normally, these tiny one-way valves keep blood flowing upward toward the heart. When they fail, blood can leak backward and collect in the veins — a process called venous reflux.

Other common causes include:

1. Damaged or Malfunctioning Valves

This is the main cause of CVI. When the valves do not close properly, gravity causes blood to flow backward (venous reflux), leading to increased pressure and swelling in the legs.

2. Deep Vein Thrombosis (DVT)

A history of deep vein thrombosis — blood clots that form in the deep veins of the legs — can damage the vein walls and valves permanently. This increases the risk of developing chronic venous insufficiency later on.

3. Weakened Vein Walls

Some people naturally have weaker vein walls, which stretch and lose elasticity over time. This can make it harder for the valves to close properly, leading to chronic venous pooling.

Risk Factors for CVI

Several factors can increase the likelihood of developing chronic venous insufficiency. These include:

  • Age: The risk increases as you get older, as veins lose elasticity with age.

  • Family History: Genetics plays a role — if your parents or siblings have varicose veins or CVI, your risk is higher.

  • Female Sex: Hormonal changes related to pregnancy, menopause, and birth control use can weaken vein walls.

  • Pregnancy: Increased blood volume and pressure during pregnancy can strain leg veins.

  • Obesity: Carrying extra weight adds pressure on leg veins, making it harder for blood to circulate properly.

  • Prolonged Sitting or Standing: Jobs that involve standing or sitting for long periods (such as teachers, drivers, or office workers) can impair blood flow in the legs.

Common Symptoms of Chronic Venous Insufficiency

CVI symptoms often develop gradually and worsen over time if untreated. The most common signs and symptoms include:

  • Pain or Aching: A dull ache, heaviness, or cramping sensation in the legs, especially after standing for long periods.

  • Swelling (Edema): Noticeable swelling in the lower legs and ankles that often improves when you elevate your legs.

  • Skin Changes: The skin may become dry, thickened, or discolored (reddish-brown or dark). Some people also develop eczema-like itching or flaking.

  • Varicose Veins: Large, twisted, or bulging veins that appear blue or purple under the skin.

  • Restless or Heavy Legs: A feeling of heaviness or fatigue in the legs, particularly in the evening.

  • Itching or Irritation: The skin around the ankles may become itchy or sensitive.

  • Leg Ulcers: In severe or untreated cases, open sores or non-healing ulcers can form near the ankles due to poor circulation.

Diagnosis of Chronic Venous Insufficiency

A healthcare professional can diagnose CVI through a physical examination and imaging tests to evaluate blood flow in the legs.

Common diagnostic methods include:

  • Physical Exam: Checking for swelling, varicose veins, and skin changes.

  • Duplex Ultrasound: The most common and effective test — it uses sound waves to visualize blood flow and identify valve dysfunction or clots.

  • CT or MRI Venography: In more complex cases, these scans can give a detailed image of deep veins and blood flow patterns.

Treatment Options for Chronic Venous Insufficiency

The treatment goal for CVI is to improve blood flow, reduce symptoms, and prevent complications. The approach depends on the severity of the condition.

1. Lifestyle Changes

  • Elevate Your Legs: Raising your legs above heart level several times a day helps reduce swelling.

  • Regular Exercise: Walking or leg-strengthening activities promote better circulation.

  • Maintain a Healthy Weight: Reducing excess body weight eases pressure on leg veins.

  • Avoid Long Periods of Sitting or Standing: Move your legs frequently to keep blood flowing.

  • Compression Stockings: Wearing medical-grade compression stockings can help squeeze the veins, improve blood flow, and reduce swelling.

2. Medications

Your doctor may prescribe:

  • Venoactive Drugs: To strengthen vein walls and improve circulation.

  • Pain Relievers or Anti-Inflammatory Medicines: To ease discomfort and inflammation.

  • Topical or Oral Medications: For managing ulcers or skin irritation.

3. Minimally Invasive Procedures

These are outpatient treatments with minimal downtime:

  • Sclerotherapy: A chemical solution is injected into small varicose or spider veins, causing them to close and fade.

  • Endovenous Laser Ablation (EVLA) or Radiofrequency Ablation (RFA): Heat energy is used to seal off damaged veins, redirecting blood flow to healthier ones.

4. Surgical Treatment

In severe or advanced cases, surgical options may be necessary:

  • Vein Ligation and Stripping: Tying off and removing damaged veins.

  • Vein Bypass Surgery: Creating a new pathway for blood flow around blocked veins.

  • Phlebectomy: Removal of large surface varicose veins through small incisions.

Complications if Left Untreated

If chronic venous insufficiency is ignored, it can lead to:

  • Venous Ulcers (non-healing wounds near the ankles)

  • Infections (due to open sores or skin breakdown)

  • Lipodermatosclerosis (hardening and tightening of the skin)

  • Permanent Skin Discoloration

Living with CVI: Prevention and Management Tips

While CVI is a chronic condition, it can be managed effectively with the right lifestyle habits and medical care.
Here are some simple tips:

  • Stay physically active — walking is one of the best exercises for vein health.

  • Avoid sitting with legs crossed for long periods.

  • Keep your legs elevated whenever possible.

  • Maintain a balanced diet low in salt and rich in fiber.

  • Follow your doctor’s advice regarding compression therapy or medications.

Conclusion

Chronic Venous Insufficiency is a common but manageable condition. Early recognition and treatment can significantly reduce discomfort, prevent complications, and improve your quality of life. If you notice symptoms like persistent leg swelling, varicose veins, or skin changes, consult a healthcare professional for evaluation and personalized treatment.


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